Hi, I am Shi, Zhilong and was born in China. I received my B.E. and M.S. degrees both in Polymer Science and Engineering from Beijing University of Chemical Technology (BUCT) in 1999 and 2002 respectively. I then obtained my PhD (Thesis Title: Conferring materials with antibacterial properties) at Department of Chemical and Biomolecular Engineering of National University of Singapore (NUS) under the supervision of Prof. Neoh KG and Prof. Kang ET in 2007 and continued to work in NUS as research fellow.
My research focuses on biological surface and functional materials for medical devices, tissue engineering/regenerative medicine, drug delivery, and marine biofouling. By investigating and understanding interfaces of materials and biological environments with biochemical and biophysical methods, I aim to effectively control and direct behavior of cells and bacteria on medical devices. My research is multidisciplinary and based on the knowledge and skills in surface functionalization, material chemistry, biology and medicine. Specially the research areas are:
- Antibacterial, anti-biofouling and anti-biofilm surface coating and biomaterials to control meidcal device-related infection and hospital-acquired infection but no toxic effects to cells, which can also be applied in marine and packaging industries.
- Bioactive and biomimetic surfaces and materials to enhance biocompability of medical devices and direct stem cell differentiation with surface physical and chemical cues. These research findings can be applied in regenerative medicine and tissue engineering.
- Biointeractive or bioselective surfaces that inhibit bacterial adhesion while enhance cellular adhesion or surfaces that can enhance orthopaedic and endothelial cell adhesion while inhibit fibroblast, smooth muscle cell and pallelet adhesion. These research findings can be applied in medical devices in orthopaedic, dental, cardiovascular, and wound healing fields which involves metal implant, bone cement, root canal sealer, stents and polymeric biomaterials.
- Multifunctional nanomaterials for bioimaging as T1/T2 contrast agents and cancer therapy with hyperthermia; liposome magnetic nanoparticles for targeted drug delivery; bioadhesive drug delivery for bladder cancer.
(Special thanks to all our collaborators in National University of Hospital (Department of Orthopaedic Surgery, Restorative Dentistry, Surgery, Diagnostic Radiology, Urology, Biochemistry), Department of Mechanical Engineering in NUS, School of Chemical and Biomedical Engineering in Nanyang Technology of University, Stem Cell Consortium and Bioimaging Consortim of A-Star, Singapore Eye Research Institute, Soochow University and Southeast University in China.)
In NUS, I have Supervised 40+ undergraduates for their final year projects and publishing 30+ papers in peer-review journals, I have rich experience in project management and applied research to solve practical problems facing in medical device, biomedicine, marine and environment .
I then moved to medical device industry to enrich my life with industrial experience in new product development. I develop:
In my spare time, I like studying history and economics (both can direct my investment in stocks and bonds); travelling with my family (since geography is my favorite in the middle school and often I got the highest score!); cooking (it is similar with doing chemistry experiments, isn't it?).
In NUS, I have Supervised 40+ undergraduates for their final year projects and publishing 30+ papers in peer-review journals, I have rich experience in project management and applied research to solve practical problems facing in medical device, biomedicine, marine and environment .
I then moved to medical device industry to enrich my life with industrial experience in new product development. I develop:
- Bioactive and antibacterial wound dressings (specially hydrogel sheet a dressings) for acute (burn, mechanical injuries) and chronic skin wound healing (diabetic food ulcer, venous ulcer, and pressure ulcer).
- Design and develop aerosol spray for wound care and healing, sunburn, disinfection and first aid.
In my spare time, I like studying history and economics (both can direct my investment in stocks and bonds); travelling with my family (since geography is my favorite in the middle school and often I got the highest score!); cooking (it is similar with doing chemistry experiments, isn't it?).
